Wally Novak arrived at Wabash in 2009, after a postdoctoral fellowship in X-ray crystallography at Brandeis University. Prof. Novak’s expertise is in the area of biochemistry and his research focuses on the study of proteins found in pathogenic bacteria, particularly transcriptional regulators and small-molecule kinases. Outside the classroom and lab, Prof. Novak is co-advisor to the Theta Delt Fraternity, and he enjoys attending faculty dinners, sporting events and the occasional game of ultimate frisbee.
In his free time, Prof. Novak enjoys spending time with his wife and three children, who can also often be found on campus. He has a variety of other interests such as cooking, astronomy, gardening, and maintaining their home which was built in 1892.
NIH Postdoctoral Fellow, Brandeis University 2004-2009
Ph.D. in Chemistry and Chemical Biology, University of California at San Francisco, 2004
B.A. summa cum laude in Chemistry, Southern Illinois University at Edwardsville, 1997
CHE 101 – Introductory Chemistry
CHE 111 – General Chemistry
CHE 221 – Organic Chemistry I
CHE 321 – Organic Chemistry II
CHE 361 – Biochemistry
CHE 461 – Special Topics in Biochemistry (recent topics include Fermentation and Nuclear Receptors)
CHE 462 – Advanced Biochemistry
Novak WR, Bhattacharyya B, Grilley DP, Weaver TM. Proteolysis of truncated hemolysin A yields a stable dimerization interface. Acta Crystallogr F Struct Biol Commun. 2017 Mar 1;73(Pt 3):138-145. Epub 2017 Feb 21.
Drury SAM, Stucker K, Douglas A, Rush RA, Novak WRP, and Wysocki LM. Using a Deliberation of Energy Policy as an Educational Tool in a Nonmajors Chemistry Course. J Chem Ed. 2016 Nov;93(11):1879-1885.
Taylor ATS, Olofson EL, Novak WRP. Enhancing student retention of prerequisite knowledge through pre-class activities and in-class reinforcement. Biochem Mol Biol Educ. 2017 Mar 4;45(2):97-104. doi: 10.1002/bmb.20992. Epub 2016 Aug 18.
Dries DR, Dean DM, Listenberger LL, Novak WRP, Franzen MA, Craig PA. An expanded framework for biomolecular visualization in the classroom: Learning goals and competencies. Biochem Mol Biol Educ. 2017 Jan-Feb; 45(1): 69–75. Epub 2016 Aug 3.
Wimmer MR, Woods CN, Adamczak KJ, Glasgow EM, Novak WR, Grilley DP, Weaver TM. Sequential unfolding of the hemolysin two-partner secretion domain from Proteus mirabilis. Protein Sci. 2015 Nov;24(11):1841-55.
Brodkin HR, DeLateur NA, Somarowthu S, Mills CL, Novak WR, Beuning PJ, Ringe D, Ondrechen MJ. Prediction of distal residue participation in enzyme catalysis. Protein Sci. 2015 May;24(5):762-78.
*Granger JB, *Lu Z, *Ferguson JB, *Santa Maria PJ, Novak WRP. Cloning, expression, purification and characterization of an iron-dependent regulator protein from Thermobifida fusca. Protein Expr Purif. 2013 Sep 29;92(2):190-194.
Andrews FH, *Tom AR, *Gunderman PR, Novak WRP, McLeish MJ. A bulky hydrophobic residue is not required to maintain the v-conformation of enzyme-bound thiamin diphosphate. Biochemistry. 2013 May 7;52(18):3028-30.
Brodkin H, Novak WRP, Milne A, D'Aquino JA, Karabacak N, Agar J, Payne M, Petsko GA, Ondrechen MJ, Ringe D. Evidence for Participation of Remote Residues in the Catalytic Activity of Co-type Nitrile Hydratase from Pseudomonas putida. Biochemistry, 2011. 50(22):4923-4935.
Lazar L, Fisher SZ, Moulin A, Kovalevsky A, Novak W, Langan P, Petsko G, Ringe D. Time of-flight neutron diffraction study of bovine gamma-chymotrypsin at the Protein Crystallography Station. Acta Crystallographica F, 2011 67:587-590.
Novak WRP, Moulin AG, Blakeley MP, Schlichting I, Petsko GA, Ringe D. A preliminary neutron diffraction study of γ-chymotrypsin. Acta Crystallographica F, 2009. 65:317-320.
*Indicates undergraduate coauthor
Full publication list can be found here.
NSF DUE Award 1140711, Co-PI with Ann Taylor - Fostering Remembering: Enhancing Student Retention of Prerequisite Knowledge through Preclass Activities and Process Oriented Guided Inquiry Integrated Case Studies $127,921
NIH Ruth L. Kirschstein NRSA Post-Doctoral Fellowship
Burroughs Wellcome Fellowship in Quantitative Biology
Phi Kappa Phi Honor Society
National Research Training Grant in Pharmaceutical Chemistry
Class of 1997 Student Speaker
Donal G. Meyer Outstanding Student in Chemistry Award
Society of Physics Student Underclassman Award
Army Achievement Medal
Army Reserve Component Achievement Medal
MAJORS & MINORS
- ASIAN STUDIES (MINOR)
- BLACK STUDIES (MINOR)
- BUSINESS (MINOR)
- COMPUTER SCIENCE (MINOR)
- EDUCATION STUDIES (MINOR)
- ELECTRONIC MUSIC (MINOR)
- ENGINEERING (DUAL-DEGREE)
- FINANCIAL ECONOMICS
- FILM AND DIGITAL MEDIA (MINOR)
- GENDER STUDIES (MINOR)
- Global Health (MINOR)
- HISPANIC STUDIES
- MODERN LANGUAGES
- MULTICULTURAL AMER. STUDIES (MINOR)
- Neuroscience (MINOR)
- PRE-MEDICINE (PRE-PROFESSIONAL)
- POLITICAL SCIENCE